Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

Makoto Orii; Takashi Kubo; Atsushi Tanaka; Hironori Kitabata; Yasushi Ino; Yasutsugu Shiono; Kunihiro Shimamura; Hiroshi Aoki; Shingo Ohta; Yuichi Ozaki; Kohei Ishibashi; Takashi Yamano; Takashi Tanimoto; Tomoyuki Yamaguchi; Kumiko Hirata; Toshio Imanishi; Takashi Akasaka

doi:10.1536/ihj.54.64

Clinical Studies

Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

Makoto Orii, Takashi Kubo, Atsushi Tanaka, Hironori Kitabata, Yasushi Ino, Yasutsugu Shiono, Kunihiro Shimamura, Hiroshi Aoki, Shingo Ohta, Yuichi Ozaki, Kohei Ishibashi, Takashi Yamano, Takashi Tanimoto, Tomoyuki Yamaguchi, Kumiko Hirata, Toshio Imanishi, Takashi Akasaka

Author information

Makoto Orii
Department of Cardiovascular Medicine, Wakayama Medical University
Takashi Kubo
Department of Cardiovascular Medicine, Wakayama Medical University
Atsushi Tanaka
Department of Cardiovascular Medicine, Wakayama Medical University
Hironori Kitabata
Department of Cardiovascular Medicine, Wakayama Medical University
Yasushi Ino
Department of Cardiovascular Medicine, Wakayama Medical University
Yasutsugu Shiono
Department of Cardiovascular Medicine, Wakayama Medical University
Kunihiro Shimamura
Department of Cardiovascular Medicine, Wakayama Medical University
Hiroshi Aoki
Department of Cardiovascular Medicine, Wakayama Medical University
Shingo Ohta
Department of Cardiovascular Medicine, Wakayama Medical University
Yuichi Ozaki
Department of Cardiovascular Medicine, Wakayama Medical University
Kohei Ishibashi
Department of Cardiovascular Medicine, Wakayama Medical University
Takashi Yamano
Department of Cardiovascular Medicine, Wakayama Medical University
Takashi Tanimoto
Department of Cardiovascular Medicine, Wakayama Medical University
Tomoyuki Yamaguchi
Department of Cardiovascular Medicine, Wakayama Medical University
Kumiko Hirata
Department of Cardiovascular Medicine, Wakayama Medical University
Toshio Imanishi
Department of Cardiovascular Medicine, Wakayama Medical University
Takashi Akasaka
Department of Cardiovascular Medicine, Wakayama Medical University

Keywords: Intracoronary imaging, Coronary artery disease

JOURNAL FREE ACCESS

2013 Volume 54 Issue 2 Pages 64-67

DOI https://doi.org/10.1536/ihj.54.64

Details

Abstract

Frequency-domain optical coherence tomography (FD-OCT) is a novel technology which provides high-resolution cross-sectional images of coronary arteries. The aim of this study was to evaluate the inter-scan reproducibility of geometric FD-OCT measurements in the clinical setting. We examined 20 coronary lesions using FD-OCT. Following the FD-OCT image acquisition (1^st pullback), and after the disengagement and re-engagement of the guiding catheter, an additional acquisition (2^nd pullback) was performed using a new FD-OCT catheter. There was excellent correlation for minimum lumen area (r = 0.99, P < 0.001), lesion length (r = 0.99, P < 0.001) and lumen volume (r = 0.99, P < 0.001) between the 1^st pullback and the 2^nd pullback. The Bland-Altman test demonstrated good agreement between the 1^st pullback and the 2^nd pullback: the mean difference for minimum lumen area, lesion length, and lumen volume was 0.05 mm², 0.03 mm, and 0.70 mm³, respectively; and the lower and upper limit of agreement for minimum lumen area, lesion length, and lumen volume was -0.58 and 0.48, -0.36 and 0.42, and -13.4 and 12.1, respectively. FD-OCT showed an excellent inter-scan reproducibility for the geometric coronary artery measurements. Our findings emphasize the value of FD-OCT as a tool for clinical longitudinal studies of coronary artery disease.

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