2013 Volume 75 Issue 1 Pages 85-88
In rodents, Gαi2-expressing sensory neurons (SNs) that co-express vomeronasal receptor type 1 (V1R) are specifically found in the vomeronasal organ (VNO) and project their axons to the accessory olfactory bulb (AOB). In goats, however, Gαi2/V1R-expressing SNs exist in both the VNO and the olfactory epithelium. Thus, we examined whether the Gαi2-expressing axons functionally project to the main olfactory bulb (MOB). We analyzed the expression of Gαi2 in the olfactory bulb and found small Gαi2-immunoreactive clusters in the MOB. The Gαi2-immunoreactive axons in these clusters made synaptic contacts with second-order neurons in the MOB. These results suggest that some Gαi2-expressing SNs functionally project their axons to the MOB in goats.