EFFECTS OF ORAL SUPPLEMENTATION OF L-ARGININE IN THE TREATMENT OF PULMONARY HYPERTENSION SECONDARY TO PULMONARY EMBOLISM: A CASE REPORT

HIROSHI OGATA; TOMOKO TAKAHASHI; KAZUNOBU ISHIKAWA; TOSIYUKI ISHIBASHI; YUKIO MARUYAMA; MACHIKO WATANABE; KIYOTO EDO

doi:10.5387/fms.56.135

Case Reports

EFFECTS OF ORAL SUPPLEMENTATION OF L-ARGININE IN THE TREATMENT OF PULMONARY HYPERTENSION SECONDARY TO PULMONARY EMBOLISM: A CASE REPORT

HIROSHI OGATA, TOMOKO TAKAHASHI, KAZUNOBU ISHIKAWA, TOSIYUKI ISHIBASHI, YUKIO MARUYAMA, MACHIKO WATANABE, KIYOTO EDO

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Keywords: L-arginine, pulmonary hypertension, brain natriuretic peptide

JOURNAL OPEN ACCESS

2010 Volume 56 Issue 2 Pages 135-138

DOI https://doi.org/10.5387/fms.56.135

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Abstract

We tried L-arginine for the treatment of pulmonary hypertension secondary to pulmonary embolism. The plasma brain natriuretic peptide (BNP) level inversely correlated with the plasma concentration of L-arginine. After oral supplementation of L-arginine, patient's symptoms (shortness of breath and general malaise), state of congestive heart failure, and exercise capacity all improved. L-arginine may be effective in the treatment of pulmonary hypertension secondary to pulmonary embolism.

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