Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Protein-Losing Enteropathy in a Case of Nodal Follicular Lymphoma without a Gastrointestinal Mucosal Lesion
Hiroto Kaneko, Mihoko Yamashita, Muneo Ohshiro, Yasuo Ohkawara, Yosuke Matsumoto, Kenichi Nomura, Shigeo Horiike, Shouhei Yokota, Masafumi Taniwaki
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Keywords: protein-losing enteropathy, follicular lymphoma
JOURNAL OPEN ACCESS

2008 Volume 47 Issue 24 Pages 2171-2173

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Abstract

Protein-losing enteropathy (PLE) is characterized by gastrointestinal loss of serum protein. It is usually caused by hypersecretion from a tumor, ulcer, or long standing lymphangiectasia. However, we report a 47-year-old man of peritoneal nodal follicular lymphoma who developed PLE with none of them. Oozing of whitish fluid from duodenal bulbar mucosa was endoscopically seen, resulting in continuous loss of protein. Chemotherapy was effective and PLE was rapidly diminished. Nodal lymphoma lesion was considered to disturb lymphatic flow and to regurgitate it to duodenal mucosa. To our knowledge, this is the second report of a lymphoma patient presenting PLE without a gastrointestinal mucosal lesion.

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© 2008 by The Japanese Society of Internal Medicine
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