Proceedings of the Japan Academy, Series B
Online ISSN : 1349-2896
Print ISSN : 0386-2208
ISSN-L : 0386-2208
Reviews
Antiparasitic agents produced by microorganisms
Kazuro SHIOMISatoshi OMURA
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2004 Volume 80 Issue 6 Pages 245-258

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Abstract

Microorganisms produce many useful antiparasitic agents. Antiparasitic activities and biochemical targets of antiprotozoal and anthelmintic antibiotics are reviewed. Antimalarial apicidin, thiolactomycin, fosmidomycin, and borrelidin, antitrypanosomal ascofuranone, and nematocidal emodepside, 2-deoxoparaherquamide A, and nafuredin are recently discovered antibiotics, and they have potential as useful drugs.


(Contributed by Satoshi OMURA, M.J.A.)

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© 2004 The Japan Academy
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