The Bulletin of Tokyo Dental College
Print ISSN : 0040-8891
Case Reports
A CASE OF AN AMELOBLASTIC FIBRO-ODONTOMA ARISING FROM A CALCIFYING ODONTOGENIC CYST
KENICHI MATSUZAKA, TAKASHI INOUE, MASANORI NASHIMOTO, KYOTO TAKEMOTO, HIROKI ISHIKAWA, MITSURU ASAKA, MASAKI SHIMONO, MAKI FUJIKAWA, HIROYASU NOMA
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Keywords: Odontogenic tumor, Ameloblastic fibro-odontoma, Calcifying odontogenic cyst, Ghost cell, Infiltration
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2001 Volume 42 Issue 1 Pages 51-55

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Abstract

This case report describes an ameloblastic fibro-odontoma arising from a calcifying odontogenic cyst (COC) in the mandible of a twenty-three-year old male. The patient was referred to the Department of Oral Surgery, Tokyo Dental College, on March 30th, 2000, complaining of a painful swelling, which had appeared three weeks earlier on his left mandibular molar region. In a pathological view, the lesion was a round cyst the size of a chicken-egg, dark red in color, and surrounded by a thick membrane. The cyst had an epithelium of varying thickness which included many ghost cells and an enamel-like structure on the inside, and a thick wall of connective tissue with an ameloblastic fibro-odontoma on the outside. Enamel organ-like epithelial islands were structured radially in the form of strands with immature dentin. Cytokeratin 19 was strongly immunoreactive in the epithelium of the lesion; osteopontin and osteocalcin reacted in the mesenchymal cells and weakly in the epithelial element of this tumor.

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© 2001 by Tokyo Dental College, Japan
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