1990 Volume 160 Issue 1 Pages 93-94
SUMI, S., ISHIKAWA, T., ITO, Y., OISHI, H., ASAI, K. and WADA, Y. Probable Assignment of the Dihydropteridine Reductase Gene to 4p15.31. Tohoku J. Exp. Med., 1990, 160 (1), 93-94-We report the dihydropteridine reductase (DHPR) activity in cases with interstitial deletion of the short arm of chromosome 4. Case 1 with the segment 4p15.32-4p16 deleted has normal DHPR activity. Case 2 with 4p15.2-4p15.32 deleted has reduced DHPR activity, less than 50% of normal.