1990 Volume 161 Issue 1 Pages 65-67
SUMI, S., OBAYASHI, M., MURAKAMI, M., ITO, J., OKADA, N. and SHIBATA, Y. Acute Megakaryoblastic Leukemia in Down Syndrome, Following Thrombocytopenia with Antiplatelet Antibody. Tohoku J. Exp. Med., 1990, 161(1), 65-67 - We report a case of acute megakaryoblastic leukemia (AMKL) with antiplatelet antibody in a boy with Down syndrome. When the patient was admitted, his platelet count was 1.3×104/mm3 and antiplatelet antibody in the plasma was detected. Two months after admission, blasts, which showed positive reaction to both antiplatelet monoclonal antibody and platelet peroxidase, increased.