The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Acute Megakaryoblastic Leukemia in Down Syndrome, Following Thrombocytopenia with Antiplatelet Antibody
SATOSHI SUMIMIKIHISA OBAYASHIMAYUMI MURAKAMIJIN ITONOBORU OKADAYOICHI SHIBATA
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1990 Volume 161 Issue 1 Pages 65-67

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Abstract

SUMI, S., OBAYASHI, M., MURAKAMI, M., ITO, J., OKADA, N. and SHIBATA, Y. Acute Megakaryoblastic Leukemia in Down Syndrome, Following Thrombocytopenia with Antiplatelet Antibody. Tohoku J. Exp. Med., 1990, 161(1), 65-67 - We report a case of acute megakaryoblastic leukemia (AMKL) with antiplatelet antibody in a boy with Down syndrome. When the patient was admitted, his platelet count was 1.3×104/mm3 and antiplatelet antibody in the plasma was detected. Two months after admission, blasts, which showed positive reaction to both antiplatelet monoclonal antibody and platelet peroxidase, increased.

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