Takotsubo Cardiomyopathy With Marked ST-Segment Elevation and Electrical Alternans Complicated With Hyperglycemic Hyperosmolar State

Kotaro Oe; Kiyoo Mori; Michio Otsuji; Tetsuo Konno; Noboru Fujino; Masakazu Yamagishi

doi:10.1536/ihj.49.629

Case Reports

Takotsubo Cardiomyopathy With Marked ST-Segment Elevation and Electrical Alternans Complicated With Hyperglycemic Hyperosmolar State

Kotaro Oe, Kiyoo Mori, Michio Otsuji, Tetsuo Konno, Noboru Fujino, Masakazu Yamagishi

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Keywords: Takotsubo cardiomyopathy, Electrical alternans, Hyperglycemic hyperosmolar state

JOURNAL FREE ACCESS

2008 Volume 49 Issue 5 Pages 629-635

DOI https://doi.org/10.1536/ihj.49.629

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Abstract

This is the first report of a case of Takotsubo cardiomyopathy with a hyperglycemic hyperosmolar state (HHS). This case presented with marked ST-segment elevation and electrical alternans, uncommon findings in Takotsubo cardiomyopathy. We believe that hyperosmolarity-induced myocardial dehydration and consequent increase in intracellular calcium concentration may be the mechanism of Takotsubo cardiomyopathy and electrical alternans in HHS.

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