1988 Volume 154 Issue 4 Pages 389-397
SHIMIZU, H., MORISHITA, M., MIZUNO, K., MASUDA, T., OGURA, Y., SANTO, M., NISHIMURA, M., KUNISHIMA, K., KARASAWA, K., NISHIWAKI, K., YAMAMOTO, M., HISAMICHI, S. and TOMINAGA, S. A Case-Control Study of Lung Cancer in Nonsmoking Women. Tohoku J. exp. Med., 1988, 154 (4), 389-397-A case-control study of Japanese women in Nagoya was conducted to investigate the significance of passive smoking and other factors in relation to the etiology of female lung cancer. A total of 90 nonsmoking patients with primary lung cancer and their age- and hospital-matched female controls were asked to fill in a questionnaire in the hospital. Elevated relative risk (RR) of lung cancer was observed for passive smoking from mother (RR=4.0; p<0.05) and from husband's father (RR=3.2; p<0.05). No association was observed between the risk of lung cancer and smoking of husband or passive smoke exposure at work. Occupational exposure to iron or other metals also showed high risk (RR=4.8; p<0.05). No appreciable differences in food intakes were observed between cases and controls.
