The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Dilatation of Cerebral Ventricles of Rat Offsprings Induced by 6-Mercaptopurine Administration to Dams
Tsuneo Arakawa, Masako Fujii, Tadashi Hayashi
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1967 Volume 91 Issue 2 Pages 143-148

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Abstract

Microcephaly and dilatation of cerebral ventricles not accompanied with other gross malformations were induced in rat offsprings by an intraperitoneal administration of 6-mercaptopurine in a dose of 24 mg/kg on the eleventh day of gestation of dams.

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